Calculate Gene Signature Enrichment With PAGE¶
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PAGEEnrich()
Function to calculate gene signature enrichment scores per spatial position using PAGE..
PAGEEnrich()
Arguments¶
Note
Arguments passed on to runPAGEEnrich()
gobject |
Giotto object |
sign_matrix |
Matrix of signature genes for each cell type / process |
expression_values |
expression values to use |
min_overlap_genes |
minimum number of overlapping genes in sign_matrix required to calculate enrichment |
reverse_log_scale |
reverse expression values from log scale |
logbase |
log base to use if reverse_log_scale = TRUE |
output_enrichment |
how to return enrichment output |
p_value |
calculate p-values (boolean, default = FALSE) |
include_depletion |
calculate both enrichment and depletion |
n_times |
number of permutations to calculate for p_value |
max_block |
number of lines to process together (default = 20e6) |
name |
to give to spatial enrichment results, default = PAGE |
verbose |
be verbose |
return_gobject |
return giotto object |
See also