Calculate Gene Signature Enrichment With PAGE

PAGEEnrich()

Function to calculate gene signature enrichment scores per spatial position using PAGE..

PAGEEnrich()

Arguments

Note

Arguments passed on to runPAGEEnrich()

gobject

Giotto object

sign_matrix

Matrix of signature genes for each cell type / process

expression_values

expression values to use

min_overlap_genes

minimum number of overlapping genes in sign_matrix required to calculate enrichment

reverse_log_scale

reverse expression values from log scale

logbase

log base to use if reverse_log_scale = TRUE

output_enrichment

how to return enrichment output

p_value

calculate p-values (boolean, default = FALSE)

include_depletion

calculate both enrichment and depletion

n_times

number of permutations to calculate for p_value

max_block

number of lines to process together (default = 20e6)

name

to give to spatial enrichment results, default = PAGE

verbose

be verbose

return_gobject

return giotto object

See also

runPAGEEnrich()