Perform DWLS Deconvolution

runDWLSDeconv()

Function to perform DWLS deconvolution based on single cell expression data.

runDWLSDeconv(
    gobject,
    expression_values = c("normalized"),
    logbase = 2,
    cluster_column = "leiden_clus",
    sign_matrix,
    n_cell = 50,
    cutoff = 2,
    name = NULL,
    return_gobject = TRUE
)

Arguments

gobject	giotto object
expression_values	expression values to use
logbase	base used for log normalization
cluster_column	name of cluster column
sign_matrix	sig matrix for deconvolution
n_cell	number of cells per spot
cutoff	cut off (default = 2)
name	name to give to spatial deconvolution results, default = DWLS
return_gobject	return giotto object

Value

A Giotto object or deconvolution results.